CST3 Protein (His tag)

Catalog No. ABIN7318374

Product Details

Target: CST3 (Cystatin C (CST3))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CST3 protein is labelled with His tag.

Purpose: Recombinant Human Cystatin C/CST3 Protein (Human Cells, His Tag)

Sequence: Ser27-Ala146

Characteristics: Recombinant Human Cystatin C is produced by our Mammalian expression system and the target gene encoding Ser27-Ala146 is expressed with a 6His tag at the C-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 10 mM PB, 200 mM Nacl, pH 6.5.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CST3 (Cystatin C (CST3))

Alternative Name: Cystatin C/CST3 (CST3 Products)

Synonyms: armd11 Protein, fb51d07 Protein, wu:fb24g06 Protein, wu:fb51d07 Protein, wu:fc55f03 Protein, zgc:136227 Protein, ARMD11 Protein, CysC Protein, CYSC Protein, cystatin C Protein, cystatin C L homeolog Protein, cystatin C (amyloid angiopathy and cerebral hemorrhage) Protein, cystatin 3 Protein, CST3 Protein, cst3.L Protein, cst3 Protein, cystatin 3 Protein, Cst3 Protein

Background:

Background: Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.

Synonym: Cystatin-C,Cystatin-3,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin,CST3

Molecular Weight: 14.4 kDa

UniProt: P01034