CTH Protein
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- Target See all CTH Proteins
- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Cystathionine γ-Lyase/CTH Protein
- Sequence
- Met 1-Ser405
- Characteristics
- Recombinant Human Cystathionine Gamma-Lyase is produced by our E.coli expression system and the target gene encoding Met1-Ser405 is expressed.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTH Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,20 % Glycerol, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
- Alternative Name
- Cystathionine gamma-Lyase/CTH (CTH Products)
- Synonyms
- DYT17 Protein, DYT18 Protein, DYT9 Protein, EIG12 Protein, GLUT Protein, GLUT1 Protein, GLUT1DS Protein, HTLVR Protein, PED Protein, wu:fb48e03 Protein, wu:fb58d08 Protein, zgc:66001 Protein, zgc:85785 Protein, CTH Protein, 0610010I13Rik Protein, AI314617 Protein, BC019483 Protein, CSE Protein, Cys3 Protein, cysA Protein, SCQ11.03c Protein, DDBDRAFT_0190313 Protein, DDBDRAFT_0191318 Protein, DDB_0190313 Protein, DDB_0191318 Protein, H Protein, MGC75946 Protein, cystathionine gamma-lyase Protein, solute carrier family 2 member 1 Protein, cystathionase (cystathionine gamma-lyase) Protein, cystathionine gamma-lyase L homeolog Protein, CTH Protein, SLC2A1 Protein, cth Protein, Cth Protein, SCO3920 Protein, mlr1566 Protein, TA_RS00415 Protein, MAP_RS15640 Protein, SPO3344 Protein, CNN01730 Protein, Mmcs_1928 Protein, RHA1_RS31820 Protein, HNE_1212 Protein, MAV_3867 Protein, MSMEG_2394 Protein, Mvan_2142 Protein, SACE_6136 Protein, Mflv_4220 Protein, cysA Protein, cth.L Protein
- Background
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Background: Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.
Synonym: Cystathionine Gamma-Lyase, Cysteine-Protein Sulfhydrase, Gamma-Cystathionase, CTH
- Molecular Weight
- 44.7 kDa
- UniProt
- P32929
- Pathways
- ER-Nucleus Signaling, Warburg Effect
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