CNTN2 Protein (His tag)
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- Target See all CNTN2 Proteins
- CNTN2 (Contactin 2 (Axonal) (CNTN2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CNTN2 protein is labelled with His tag.
- Purpose
- Recombinant Human Contactin 2/CNTN2 Protein (His Tag)
- Sequence
- Ser31-Asn1012
- Characteristics
- Recombinant Human Transient axonal glycoprotein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Asn1012 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CNTN2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CNTN2 (Contactin 2 (Axonal) (CNTN2))
- Alternative Name
- Contactin 2/CNTN2 (CNTN2 Products)
- Synonyms
- tag1 Protein, si:dz37k09.2 Protein, CNTN2 Protein, D130012K04Rik Protein, TAG-1 Protein, Tax Protein, AXT Protein, TAX Protein, TAX1 Protein, AXONIN-1 Protein, TAG-564 Protein, TAG1 Protein, contactin 2 Protein, contactin 2 (axonal) Protein, cntn2 Protein, CNTN2 Protein, Cntn2 Protein
- Background
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Background: Contactin-2 (CNTN2) is encoded by the CNTN2 gene,which belongs to the immunoglobulin superfamily and contactin family. It contains 4 fibronectin type-III domains and 6 Ig-like C2-type domains. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. CNTN2 may play a role in the formation of axon connections in the developing nervous system. In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
Synonym: Contactin-2, Axonal glycoprotein TAG-1, Axonin-1, Transient axonal glycoprotein 1, CNTN2, AXT, TAG1, TAX1
- Molecular Weight
- 108.7 kDa
- UniProt
- Q02246
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
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