CTGF Protein
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- Target See all CTGF Proteins
- CTGF (Connective Tissue Growth Factor (CTGF))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purpose
- Recombinant Human CTGF/CCN2 Protein
- Sequence
- Glu27-Ala180
- Characteristics
- Recombinant Human Connective tissue growth factor is produced by our Mammalian expression system and the target gene encoding Glu27-Ala180 is expressed.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTGF Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CTGF (Connective Tissue Growth Factor (CTGF))
- Alternative Name
- CTGF/CCN2 (CTGF Products)
- Background
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Background: CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).
Synonym: Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8
- Molecular Weight
- 16.3 kDa
- UniProt
- P29279
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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