Coagulation Factor IX Protein (F9) (His tag)

Catalog No. ABIN7317553

Product Details

Target: Coagulation Factor IX (F9)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Coagulation Factor IX protein is labelled with His tag.

Purpose: Recombinant Human Coagulation Factor IX/F9 Protein (His Tag)(Active)

Sequence: Met 1-Thr 461

Characteristics: A DNA sequence encoding the human F9 (AAB59620.1) (Met 1-Thr 461) was expressed, fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its ability to cleave the peptide substrate, Z-D-Arg-Gly-Arg-pNA. The specific activity is >20pmols/min/ug.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Coagulation Factor IX (F9)

Alternative Name: Coagulation Factor IX/F9 (F9 Products)

Synonyms: AA407498 Protein, AI506714 Protein, AK-3 Protein, Ak3l Protein, Ak3l1 Protein, Akl3l Protein, FIX Protein, HEMB Protein, P19 Protein, PTC Protein, THPH8 Protein, AW111646 Protein, Cf-9 Protein, Cf9 Protein, f9 Protein, zgc:109775 Protein, fix Protein, ptc Protein, hemb Protein, FIXA Protein, zgc:136807 Protein, adenylate kinase 3 Protein, coagulation factor IX Protein, coagulation factor IXa Protein, coagulation factor 9 Protein, coagulation factor 9 S homeolog Protein, Coagulation factor IX Protein, coagulation factor IXb Protein, Ak3 Protein, F9 Protein, f9a Protein, f9 Protein, CpipJ_CPIJ003776 Protein, CpipJ_CPIJ009129 Protein, CpipJ_CPIJ013063 Protein, CpipJ_CPIJ013624 Protein, Tsp_01441 Protein, f9.S Protein, fa9 Protein, f9b Protein

Background:

Background: Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.

Synonym: Coagulation factor 9,F9,Coagulation factor IX,Christmas factor,Plasma thromboplastin component,Coagulation factor IXa light chain,Coagulation factor IXa heavy chain,FIX,HEMB,P19,PTC,THPH8

Molecular Weight: 50 kDa