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Claudin 11 Protein (CLDN11) (Fc Tag)

CLDN11 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317330
  • Target See all Claudin 11 (CLDN11) Proteins
    Claudin 11 (CLDN11)
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Claudin 11 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human CLDN11/Claudin-11 Protein (Fc Tag)
    Sequence
    Val23-Arg82
    Characteristics
    A DNA sequence encoding the human CLDN11 (O75508) (Val23-Arg82) was expressed with the Fc region of mouse IgG1 at the N-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CLDN11 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Claudin 11 (CLDN11)
    Alternative Name
    CLDN11/Claudin-11 (CLDN11 Products)
    Synonyms
    cldn11 Protein, fb97c11 Protein, wu:fb97c11 Protein, claudin-11 Protein, CLDN11 Protein, Claudin-11 Protein, DKFZp459H2322 Protein, OSP Protein, OTM Protein, Claudin11 Protein, Osp Protein, Otm Protein, claudin 11b Protein, claudin 11 Protein, cldn11b Protein, CLDN11 Protein, Cldn11 Protein
    Background

    Background: Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.Claudin-11 is a tight junction associated protein and is a major component of central nervous system (CNS) myelin that is necessary for normal CNS function. Human blood-testis barrier disruption is related to a dysfunction of CLDN11 gene. It plays an important role in regulating proliferation and migration of oligodendrocytes.

    Synonym: OSP,OTM

    Molecular Weight
    33.2 kDa
    UniProt
    O75508
    Pathways
    Hepatitis C
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