Claudin 11 Protein (CLDN11) (Fc Tag)
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- Target See all Claudin 11 (CLDN11) Proteins
- Claudin 11 (CLDN11)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Claudin 11 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CLDN11/Claudin-11 Protein (Fc Tag)
- Sequence
- Val23-Arg82
- Characteristics
- A DNA sequence encoding the human CLDN11 (O75508) (Val23-Arg82) was expressed with the Fc region of mouse IgG1 at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CLDN11 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Claudin 11 (CLDN11)
- Alternative Name
- CLDN11/Claudin-11 (CLDN11 Products)
- Synonyms
- cldn11 Protein, fb97c11 Protein, wu:fb97c11 Protein, claudin-11 Protein, CLDN11 Protein, Claudin-11 Protein, DKFZp459H2322 Protein, OSP Protein, OTM Protein, Claudin11 Protein, Osp Protein, Otm Protein, claudin 11b Protein, claudin 11 Protein, cldn11b Protein, CLDN11 Protein, Cldn11 Protein
- Background
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Background: Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.Claudin-11 is a tight junction associated protein and is a major component of central nervous system (CNS) myelin that is necessary for normal CNS function. Human blood-testis barrier disruption is related to a dysfunction of CLDN11 gene. It plays an important role in regulating proliferation and migration of oligodendrocytes.
Synonym: OSP,OTM
- Molecular Weight
- 33.2 kDa
- UniProt
- O75508
- Pathways
- Hepatitis C
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