CCL24 Protein
-
- Target See all CCL24 Proteins
- CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
- Protein Type
- Recombinant
-
Origin
- Mouse
-
Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Mouse CCL24/Eotaxin-2 Protein
- Sequence
- Val27-Val119
- Characteristics
- Recombinant Mouse C-C Motif Chemokine 24 is produced by our E.coli expression system and the target gene encoding Val27-Val119 is expressed.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CCL24 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
- Alternative Name
- CCL24/Eotaxin-2 (CCL24 Products)
- Background
-
Background: Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58 % amino acid sequence identity with human Ccl24. It is predominantly expressed in the jejunum and spleen and also be induced in the lung by allergen challengeand IL4. Mouse ccl24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Ccl24 is chemotactic for resting T-lymphocytes, eosinophils and can bind to CCR3. LPS and IL4 also differentially regulate the expression of Ccl24 in monocytes and macrophages.
Synonym: C-C motif chemokine 24,Ccl24,Eosinophil chemotactic protein 2,Eotaxin-2,Small-inducible cytokine A24,Scya24
- Molecular Weight
- 10.3 kDa
- UniProt
- Q9JKC0
- Pathways
- Regulation of Actin Filament Polymerization
-