Ccl21a Protein
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- Target See all Ccl21a (CCL21A) Proteins
- Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))
- Protein Type
- Recombinant
- Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Mouse CCL21a Protein
- Sequence
- Ser24-Gly133
- Characteristics
- Recombinant Mouse C-C Motif Chemokine 21a is produced by our E.coli expression system and the target gene encoding Ser24-Gly133 is expressed.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CCL21A Protein
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Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A) (AA 24-133) protein (His tag)
CCL21A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))
- Alternative Name
- CCL21a (CCL21A Products)
- Background
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Background: C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.
Synonym: C-C Motif Chemokine 21a, 6Ckine, Beta-Chemokine Exodus-2, Small-Inducible Cytokine A21a, Thymus-Derived Chemotactic Agent 4, TCA4, Ccl21a, Scya21, Scya21a
- Molecular Weight
- 12.0 kDa
- UniProt
- P84444
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