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CD96 Protein (CD96) (His tag)

CD96 Origin: Human Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7319442
  • Target See all CD96 Proteins
    CD96
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 14
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CD96 protein is labelled with His tag.
    Purpose
    Recombinant Human CD96 Protein (His Tag)(Active)
    Sequence
    Val22-Met503
    Characteristics
    Recombinant Human CD96 is produced by our Mammalian expression system and the target gene encoding Val22-Met503 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human PVR-His(Cat: PKSH033563) at 10μg/ml(100 μl/well) can bind Biotinylated Human CD96-His. The ED50 of Human CD96-His is 27.54μg/mL.
    Top Product
    Discover our top product CD96 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD96
    Alternative Name
    CD96 (CD96 Products)
    Synonyms
    1700109I12Rik Protein, Tactile Protein, TACTILE Protein, CD96 antigen Protein, CD96 molecule Protein, Cd96 Protein, CD96 Protein
    Background

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), anectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells.

    Synonym: T-cell surface protein tactile, Cell surface antigen CD96, T cell-activated increased late expression protein, CD96

    Molecular Weight
    54.4 kDa
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