CD72 Protein (TRX tag,His tag)
-
- Target See all CD72 Proteins
- CD72 (CD72 Molecule (CD72))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CD72 protein is labelled with TRX tag,His tag.
- Purpose
- Recombinant Human CD72/Lyb-2 Protein (Trx&His)
- Sequence
- Arg117-Cys226
- Characteristics
- Recombinant Human B-Cell Differentiation Antigen CD72 is produced by our E.coli expression system and the target gene encoding Arg117-Cys226 is expressed with a Trx, 6His tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD72 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- CD72 (CD72 Molecule (CD72))
- Alternative Name
- CD72/Lyb-2 (CD72 Products)
- Synonyms
- CD72c Protein, Ly-19 Protein, Ly-32 Protein, Ly-m19 Protein, Lyb-2 Protein, CD72b Protein, LYB2 Protein, CD72 antigen Protein, CD72 molecule Protein, Cd72 Protein, CD72 Protein
- Background
-
Background: B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.
Synonym: B-Cell Differentiation Antigen CD72, Lyb-2, CD72
- Molecular Weight
- 30.6 kDa
- UniProt
- P21854
- Pathways
- BCR Signaling
-