CD70 Protein (His tag)
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- Target See all CD70 Proteins
- CD70 (CD70 Molecule (CD70))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This CD70 protein is labelled with His tag.
- Purpose
- Recombinant Mouse CD27 Ligand/TNFSF7/CD70 (N-10His)
- Sequence
- Gln47-Pro195
- Characteristics
- Recombinant Mouse CD27 Ligand/CD70 is produced by our Mammalian expression system and the target gene encoding Gln47-Pro195 is expressed with a 10His tag at the N-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD70 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD70 (CD70 Molecule (CD70))
- Alternative Name
- CD27 Ligand/TNFSF7/CD70 (CD70 Products)
- Synonyms
- CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
- Background
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Background: CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64 % aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Synonym: CD70 antigen, CD70, CD27 ligand, Tumor necrosis factor ligand superfamily member 7, CD27LG, TNFSF7, CD27L
- Molecular Weight
- 19 kDa
- UniProt
- Q05A52
- Pathways
- Cancer Immune Checkpoints
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