Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD70 Protein (His tag)

CD70 Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320908
  • Target See all CD70 Proteins
    CD70 (CD70 Molecule (CD70))
    Protein Type
    Recombinant
    Origin
    • 30
    • 7
    • 1
    • 1
    • 1
    Mouse
    Source
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CD70 protein is labelled with His tag.
    Purpose
    Recombinant Mouse CD27 Ligand/TNFSF7/CD70 (N-10His)
    Sequence
    Gln47-Pro195
    Characteristics
    Recombinant Mouse CD27 Ligand/CD70 is produced by our Mammalian expression system and the target gene encoding Gln47-Pro195 is expressed with a 10His tag at the N-terminus.
    Purity
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD70 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD70 (CD70 Molecule (CD70))
    Alternative Name
    CD27 Ligand/TNFSF7/CD70 (CD70 Products)
    Synonyms
    CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
    Background

    Background: CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64 % aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

    Synonym: CD70 antigen, CD70, CD27 ligand, Tumor necrosis factor ligand superfamily member 7, CD27LG, TNFSF7, CD27L

    Molecular Weight
    19 kDa
    UniProt
    Q05A52
    Pathways
    Cancer Immune Checkpoints
You are here:
Support