CD160 Protein (CD160) (His tag)
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- Target See all CD160 Proteins
- CD160
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This CD160 protein is labelled with His tag.
- Purpose
- Recombinant Mouse CD160/BY55 Protein (His Tag)
- Sequence
- Gly28-Ser160
- Characteristics
- Recombinant Mouse CD160 is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD160 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD160
- Alternative Name
- CD160/BY55 (CD160 Products)
- Synonyms
- CD160 Protein, RGD1563598 Protein, BY55 Protein, AU045688 Protein, By55 Protein, NK1 Protein, NK28 Protein, CD160 molecule Protein, CD160 antigen Protein, CD160 Protein, Cd160 Protein
- Background
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Background: CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.
Synonym: CD160 Antigen, Natural Killer Cell Receptor BY55, CD160, BY55
- Molecular Weight
- 15.8 kDa
- UniProt
- Q8VC80
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