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CD160 Protein (CD160) (His tag)

CD160 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320849
  • Target See all CD160 Proteins
    CD160
    Protein Type
    Recombinant
    Origin
    • 12
    • 3
    • 2
    Mouse
    Source
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CD160 protein is labelled with His tag.
    Purpose
    Recombinant Mouse CD160/BY55 Protein (His Tag)
    Sequence
    Gly28-Ser160
    Characteristics
    Recombinant Mouse CD160 is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD160 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD160
    Alternative Name
    CD160/BY55 (CD160 Products)
    Synonyms
    CD160 Protein, RGD1563598 Protein, BY55 Protein, AU045688 Protein, By55 Protein, NK1 Protein, NK28 Protein, CD160 molecule Protein, CD160 antigen Protein, CD160 Protein, Cd160 Protein
    Background

    Background: CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.

    Synonym: CD160 Antigen, Natural Killer Cell Receptor BY55, CD160, BY55

    Molecular Weight
    15.8 kDa
    UniProt
    Q8VC80
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