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CD16 Protein (CD16) (His tag)

CD16 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320834
  • Target See all CD16 Proteins
    CD16
    Protein Type
    Recombinant
    Origin
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 5
    • 3
    • 1
    Human Cells
    Purification tag / Conjugate
    This CD16 protein is labelled with His tag.
    Purpose
    Recombinant Mouse CD16/FCGR3 Protein (His Tag)
    Sequence
    Leu32-Thr215
    Characteristics
    Recombinant Mouse CD16 is produced by our Mammalian expression system and the target gene encoding Leu32-Thr215 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD16
    Alternative Name
    CD16/FCGR3 (CD16 Products)
    Synonyms
    Fcgr3 Protein, Fcgr3a Protein, CD16 Protein, FCGR3 Protein, FCGR3@ Protein, CD16b Protein, FCG3 Protein, FCR-10 Protein, FCRIII Protein, FCRIIIb Protein, FcRIII Protein, Fc fragment of IgG, low affinity IIa, receptor Protein, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) Protein, Fc fragment of IgG receptor IIIb Protein, Fc fragment of IgG receptor IIIa Protein, Fc receptor, IgG, low affinity III Protein, Fc-gamma RIII Protein, Fcgr2a Protein, FCGR3A Protein, FCGR3B Protein, Fcgr3 Protein, FCGR3 Protein
    Background

    Background: Low affinity immunoglobulin gamma Fc region receptor III (Fc gamma RIII/CD16) is a member of the Ig superfamily. Based on close relationships in their extracellular domains, the Fc gamma Rs have been divided into three classes composing of Fc gamma RI (CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Mouse CD16 is a type I transmembrane protein having two extracellular Ig-like domains consisting of immunoglobulin domain, repeat, signa and transmembrane, transmembrane helix. It is expressed on a variety of myeloid and lymphoid cells and associates with Fc R gamma to deliver an activating signal upon ligand binding. Fcgr3 is IgG binding and activation or inhibition of immune responses such as antibody-dependent cellular cytotoxicity, phagocytosis, cell surface receptor signaling pathway and positive regulation of type I/IIa/III hypersensitivity.

    Synonym: Low affinity immunoglobulin gamma Fc region receptor III, Fcgr3, Fc gamma Receptor III, CD-antigen 16, CD16, FcRIII, IgG Fc receptor III

    Molecular Weight
    21.9 kDa
    UniProt
    Q5D5I8
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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