Cathepsin Z Protein (CTSZ) (His tag)
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- Target See all Cathepsin Z (CTSZ) Proteins
- Cathepsin Z (CTSZ)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Cathepsin Z protein is labelled with His tag.
- Purpose
- Recombinant Human Cathepsin Z Protein (His Tag)
- Sequence
- Gly24-Val303
- Characteristics
- Recombinant Human Cathepsin Z is produced by our Mammalian expression system and the target gene encoding Gly24-Val303 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTSZ Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Cathepsin Z (CTSZ)
- Alternative Name
- Cathepsin Z (CTSZ Products)
- Synonyms
- wu:fj81f10 Protein, zgc:103420 Protein, CTSZ Protein, CTSX Protein, AI787083 Protein, AU019819 Protein, D2Wsu143e Protein, CATX Protein, CathePsin Z Protein, cathepsin Z Protein, cathepsin Z S homeolog Protein, papain family cysteine protease Protein, cpz-1 Protein, cpz-2 Protein, CTSZ Protein, ctsz Protein, ctsz.S Protein, TTHERM_00102779 Protein, NAEGRDRAFT_78125 Protein, Ctsz Protein
- Background
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Background: Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence, a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B, it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family, Cathepsin Z may be involved in tumorigenesis.
Synonym: Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ
- Molecular Weight
- 32.5 kDa
- UniProt
- Q9UBR2
- Pathways
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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