Cathepsin S Protein (CTSS) (His tag)
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- Target See all Cathepsin S (CTSS) Proteins
- Cathepsin S (CTSS)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Cathepsin S protein is labelled with His tag.
- Purpose
- Recombinant Human Cathepsin S/CTSS Protein (His Tag)(Active)
- Sequence
- Gln17-Ile331(pro)&Ser109-Ile331&Gln17-Ser109(Propeptide )
- Characteristics
- Recombinant Human Cathepsin S is produced by our Mammalian expression system and the target geneencoding Gln17-Ile331(pro)&Ser109-Ile331&Gln17-Ser109(Propeptide) is expressed with a 6His tag atthe C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 The specific activity is 9063.642 pmol/min/μg.
- Top Product
- Discover our top product CTSS Protein
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Cathepsin S (CTSS) (AA 1-331) protein (GST tag)
CTSS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin S (CTSS) proteinCTSS Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Cathepsin S (CTSS) protein (His tag)CTSS Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cathepsin S (CTSS) (Active) protein (His tag)CTSS Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, 10 % Glycerol, pH 5.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Cathepsin S (CTSS)
- Alternative Name
- Cathepsin S/CTSS (CTSS Products)
- Synonyms
- ctss-a Protein, MGC69026 Protein, ctss-b Protein, MGC80097 Protein, ctss.1 Protein, CTSS Protein, ctss Protein, cats Protein, cathepsin S Protein, cathepsin S L homeolog Protein, cathepsin S S homeolog Protein, Cathepsin S Protein, CTSS Protein, Ctss Protein, ctss.L Protein, ctss.S Protein, ctss Protein, cats Protein
- Background
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Background: Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, LandH, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease(AD) and Down Syndrome (DS).
Synonym: Cathepsin S,CTSS,CTSS,MGC3886
- Molecular Weight
- 36.9&25&11.2 kDa
- UniProt
- P25774
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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