Cathepsin L2 Protein (CTSL2) (His tag)

Catalog No. ABIN7318256

Product Details

Target: Cathepsin L2 (CTSL2)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Cathepsin L2 protein is labelled with His tag.

Purpose: Recombinant Human Cathepsin L2/CTSL2 Protein (His Tag)

Sequence: Val18-Val334

Characteristics: Recombinant Human Cathepsin L2/Cathepsin V is produced by our Mammalian expression system and the target gene encoding Val18-Val334 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Cathepsin L2 (CTSL2)

Alternative Name: Cathepsin L2/CTSL2 (CTSL2 Products)

Synonyms: CATL2 Protein, CTSL2 Protein, CTSU Protein, CTSL Protein, CTSL1 Protein, ctsl2 Protein, LOC100232421 Protein, cathepsin V Protein, cathepsin V L homeolog Protein, cathepsin L Protein, CTSV Protein, ctsv.L Protein, ctsv Protein, CTSL Protein, Ctsv Protein

Background:

Background: Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically convertedto the mature form as a proenzyme in lysosomes at pH =7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.

Synonym: Cathepsin L2, Cathepsin U, Cathepsin V, CTSL2, CATL2, CTSU, CTSV

Molecular Weight: 36.7 kDa

UniProt: O60911

Pathways: Toll-Like Receptors Cascades