Cathepsin L Protein (His tag)

Catalog No. ABIN7318255

Product Details

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Cathepsin L protein is labelled with His tag.

Purpose: Recombinant Human Cathepsin L/CTSL Protein (His Tag)

Sequence: Thr18-Val333

Characteristics: Recombinant Human Cathepsin L is produced by our Mammalian expression system and the target gene encoding Thr18-Val333 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Alternative Name: Cathepsin L/CTSL (CTSL1 Products)

Synonyms: CATL Protein, CTSL1 Protein, MEP Protein, 1190035F06Rik Protein, Ctsl1 Protein, fs Protein, nkt Protein, CATHL Protein, CatL Protein, Ctsl Protein, CTSL Protein, mep Protein, catl Protein, ctsl Protein, cpl-1 Protein, MGC80629 Protein, MGC107932 Protein, LOC663234 Protein, 26-29-p Protein, Cp1 Protein, si:dkey-121a11.6 Protein, CTSV Protein, catL Protein, cb15 Protein, ctsl1b Protein, hgg1 Protein, wu:fb30g09 Protein, zgc:92089 Protein, cathepsin L Protein, cathepsin V Protein, cathepsin L L homeolog Protein, cathepsin L1 Protein, Cathepsin L1 Protein, Cathepsin L Protein, testin gene Protein, cathepsin 12 Protein, cathepsin Lb Protein, cathepsin L.1 Protein, CTSL Protein, Ctsl Protein, CTSV Protein, ctsl.L Protein, ctsl Protein, LOC100008830 Protein, catl1 Protein, 26-29-p Protein, catl Protein, Tsp_11596 Protein, Testin Protein, cts12 Protein, LOC102156614 Protein, ctslb Protein, ctsl.1 Protein

Background:

Background: Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the major excreted protein of malignantly transformed mouse fibroblasts and is also one of the major acidic cysteine proteases in mammalian cells.

Synonym: Cathepsin L1, Major Excreted Protein, MEP, CTSL1, CTSL

Molecular Weight: 36.9 kDa

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades