Cathepsin E Protein (CTSE) (His tag)

Catalog No. ABIN7321057

Product Details

Target: Cathepsin E (CTSE)

Protein Type: Recombinant

Origin: Rat

Source: HEK-293 Cells

Purification tag / Conjugate: This Cathepsin E protein is labelled with His tag.

Purpose: Recombinant Rat Cathepsin E/CTSE Protein (His Tag)

Sequence: Met1-Pro398

Characteristics: A DNA sequence encoding the rat Ctse (AAH62002.1) (Met1-Pro398) was expressed with a polyhistidine tag at the C-terminus.

Purity: > 90 % as determined by SDS-PAGE

Endotoxin Level: < 1.0 EU per μg protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 12.5 mM MES, 75 mM NaCl, 50 % glycerol, pH 6.5

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Cathepsin E (CTSE)

Alternative Name: Cathepsin E/CTSE (CTSE Products)

Synonyms: CATE Protein, A430072O03Rik Protein, C920004C08Rik Protein, CE Protein, CatE Protein, CEA Protein, CEB Protein, Ctsea Protein, CTSE Protein, ce1 Protein, ce2 Protein, cate Protein, CE1 Protein, ce1-A Protein, ctse Protein, CE2 Protein, ce2-A Protein, cathepsin E Protein, cathepsin E L homeolog Protein, cathepsin E S homeolog Protein, CTSE Protein, Ctse Protein, TP03_0056 Protein, Smp_184930 Protein, ctse Protein, ctse.L Protein, ctse.S Protein

Background:

Background: Cathepsin E Protein (CTSE Protein) is a member of the peptidase C1 family that is a gastric aspartic protease that functions as a disulfide-linked homodimer. Cathepsin E Protein (CTSE Protein) is predominantly present in the cells of immune system and is frequently implicated in antigen processing via the MHC classII pathway which however does not appear to be involved in the digestion of dietary protein. The protein has a specificity similar to that of pepsin and pepsin. Cathepsin E Protein (CTSE Protein) is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach and also been found in more than half of the gastric cancers. It appears, therefore, to be an oncofetal antigen.

Synonym: Cathepsin E,CTSE

Molecular Weight: 42.1 kDa