Cathepsin B Protein (CTSB) (His tag)
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- Target See all Cathepsin B (CTSB) Proteins
- Cathepsin B (CTSB)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Cathepsin B protein is labelled with His tag.
- Purpose
- Recombinant Human Cathepsin B/CTSB Protein (His Tag)
- Sequence
- Arg18-Ile339
- Characteristics
- Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTSB Protein
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Cathepsin B (CTSB) (AA 1-339) protein (GST tag)
CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin B (CTSB) (AA 224-333) protein (GST tag)CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin B (CTSB) (AA 21-339) protein (GST tag)CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin B (CTSB) protein (His tag)CTSB Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cathepsin B (CTSB) (Active) protein (His tag)CTSB Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Cathepsin B (CTSB) protein (His tag)CTSB Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Cathepsin B (CTSB) (AA 18-339) protein (His tag)CTSB Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Cathepsin B (CTSB) (AA 82-333), (partial) protein (GST tag)CTSB Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Cathepsin B (CTSB)
- Alternative Name
- Cathepsin B/CTSB (CTSB Products)
- Synonyms
- APPS Protein, CPSB Protein, CB Protein, apps Protein, cpsb Protein, LOC692390 Protein, CTSB Protein, cathepsin B Protein, cathepsin B S homeolog Protein, CTSB Protein, Ctsb Protein, ctsb.S Protein, LOC692390 Protein
- Background
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Background: Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
Synonym: Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB
- Molecular Weight
- 36.9 kDa
- UniProt
- P07858
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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