CROT Protein (His tag)
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- Target See all CROT Proteins
- CROT (Carnitine O-Octanoyltransferase (CROT))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CROT protein is labelled with His tag.
- Purpose
- Recombinant Human CROT Protein (474 Leu/Val, His Tag)
- Sequence
- Met 1-Leu 612, 474 Leu/Val
- Characteristics
- A DNA sequence encoding the human CROT (Q9UKG9) (Met 1-Leu 612, 474 Leu/Val) was fused with a polyhistidine tag at the C-terminus.
- Purity
- > 93 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CROT Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CROT (Carnitine O-Octanoyltransferase (CROT))
- Alternative Name
- CROT (CROT Products)
- Synonyms
- CROT Protein, cot Protein, zgc:110643 Protein, COT Protein, 1200003H03Rik Protein, carnitine O-octanoyltransferase Protein, CROT Protein, crot Protein, Crot Protein
- Background
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Background: Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain acyltransferase, is a carnitine acyltransferase belonging to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. Carnitine octanoyltransferase (CROT or COT) facilitate the transport of medium- and long-chain fatty acids through the peroxisomal and mitochondrial membranes. It is physiologically inhibited by malonyl-CoA. COT also has functions in efficiently converting one of the end products of the peroxisomal beta-oxidation of pristanic acid, 4, 8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.
Synonym: COT
- Molecular Weight
- 71.5 kDa
- UniProt
- Q9UKG9
- Pathways
- Monocarboxylic Acid Catabolic Process
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