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CROT Protein (His tag)

CROT Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 93 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317695
  • Target See all CROT Proteins
    CROT (Carnitine O-Octanoyltransferase (CROT))
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This CROT protein is labelled with His tag.
    Purpose
    Recombinant Human CROT Protein (474 Leu/Val, His Tag)
    Sequence
    Met 1-Leu 612, 474 Leu/Val
    Characteristics
    A DNA sequence encoding the human CROT (Q9UKG9) (Met 1-Leu 612, 474 Leu/Val) was fused with a polyhistidine tag at the C-terminus.
    Purity
    > 93 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CROT Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CROT (Carnitine O-Octanoyltransferase (CROT))
    Alternative Name
    CROT (CROT Products)
    Synonyms
    CROT Protein, cot Protein, zgc:110643 Protein, COT Protein, 1200003H03Rik Protein, carnitine O-octanoyltransferase Protein, CROT Protein, crot Protein, Crot Protein
    Background

    Background: Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain acyltransferase, is a carnitine acyltransferase belonging to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. Carnitine octanoyltransferase (CROT or COT) facilitate the transport of medium- and long-chain fatty acids through the peroxisomal and mitochondrial membranes. It is physiologically inhibited by malonyl-CoA. COT also has functions in efficiently converting one of the end products of the peroxisomal beta-oxidation of pristanic acid, 4, 8-dimethylnonanoyl-CoA, to its corresponding carnitine ester. 

    Synonym: COT

    Molecular Weight
    71.5 kDa
    UniProt
    Q9UKG9
    Pathways
    Monocarboxylic Acid Catabolic Process
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