CES1 Protein (His tag)
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- Target See all CES1 Proteins
- CES1 (Carboxylesterase 1 (CES1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CES1 protein is labelled with His tag.
- Purpose
- Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag)
- Sequence
- His19-Glu562
- Characteristics
- Recombinant Human Carboxylesterase 1 is produced by our Mammalian expression system and the target gene encoding His19-Glu562 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CES1 Protein
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Carboxylesterase 1 (CES1) (AA 1-566) protein (GST tag)
CES1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Carboxylesterase 1 (CES1) (Transcript Variant 2) protein (His tag)CES1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Carboxylesterase 1 (CES1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CES1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Carboxylesterase 1 (CES1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)CES1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Carboxylesterase 1 (CES1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CES1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- CES1 (Carboxylesterase 1 (CES1))
- Alternative Name
- Carboxylesterase 1/CES1 (CES1 Products)
- Synonyms
- ACAT Protein, CE-1 Protein, CEH Protein, CES2 Protein, HMSE Protein, HMSE1 Protein, PCE-1 Protein, REH Protein, SES1 Protein, TGH Protein, hCE-1 Protein, CESDD1 Protein, CES1 Protein, CES-K1 Protein, APLE Protein, PMPMEase Protein, CES Protein, carboxylesterase 1 Protein, liver carboxylesterase 1 Protein, liver carboxylesterase Protein, carboxylesterase 1 (monocyte/macrophage serine esterase 1) Protein, CES1 Protein, CpipJ_CPIJ013026 Protein, CpipJ_CPIJ016339 Protein, LOC100009551 Protein, LOC454097 Protein, LOC699486 Protein, LOC100050915 Protein
- Background
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Background: Carboxylesterase 1 (CES1) is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds. These enzymes have broad substrate specificity ranging from small molecule esters such as phenylester to long chain fatty acid esters and thioesters. They are major determinants of the pharmacokinetic behavior of most therapeutic agents containing an ester or amide bond. CES1 shares the serine hydrolase fold observed in other esterases. CES1 hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. CES1 participates in detoxification of drugs such as cocaine and heroin in serum and liver. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds.
Synonym: Liver Carboxylesterase 1, Acyl-Coenzyme A:Cholesterol Acyltransferase, ACAT, Brain Carboxylesterase hBr1, Carboxylesterase 1, CE-1, hCE-1, Cocaine Carboxylesterase, Egasyn, HMSE, Methylumbelliferyl-Acetate Deacetylase 1, Monocyte/Macrophage Serine Esterase, Retinyl Ester Hydrolase, REH, Serine Esterase 1, Triacylglycerol Hydrolase, TGH, CES1, CES2, SES1
- Molecular Weight
- 61.1 kDa
- Pathways
- Monocarboxylic Acid Catabolic Process
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