CA8 Protein (His tag)
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- Target See all CA8 Proteins
- CA8 (Carbonic Anhydrase VIII (CA8))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CA8 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Carbonic Anhydrase VIII/CA8 Protein (His Tag)(Active)
- Sequence
- Met 1-Gln 291
- Characteristics
- A DNA sequence encoding the mouse CA8 (P28651) (Met 1-Gln 291) was expressed, with a C-terminal polyhistidine tag.
- Purity
- > 88 % as determined by SDS-PAGE
- Biological Activity Comment
- Measured by its esterase activity. The specific activity is >5 pmoles/min/μg.
- Top Product
- Discover our top product CA8 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CA8 (Carbonic Anhydrase VIII (CA8))
- Alternative Name
- Carbonic Anhydrase VIII/CA8 (CA8 Products)
- Synonyms
- AW546993 Protein, Ca8 Protein, Cals Protein, Cals1 Protein, Carp Protein, wdl Protein, zgc:110118 Protein, CA-VIII Protein, CALS Protein, CAMRQ3 Protein, CARP Protein, carbonic anhydrase 8 Protein, carbonic anhydrase VIII Protein, CAH8 Protein, Car8 Protein, ca8 Protein, CA8 Protein
- Background
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Background: The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78 % of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.
Synonym: AW546993,Ca8,Cals,Cals1,Car8,Carp,RP23-180H12.1,wdl
- Molecular Weight
- 34.5 kDa
- UniProt
- P28651
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