CA4 Protein (His tag)
-
- Target See all CA4 Proteins
- CA4 (Carbonic Anhydrase IV (CA4))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CA4 protein is labelled with His tag.
- Purpose
- Recombinant Human Carbonic Anhydrase 4/CA4 Protein (His Tag)
- Sequence
- Ala19-Lys283
- Characteristics
- Recombinant Human Carbonic Anhydrase 4 is produced by our E.coli expression system and the target gene encoding Ala19-Lys283 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CA4 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, pH 8.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- CA4 (Carbonic Anhydrase IV (CA4))
- Alternative Name
- Carbonic Anhydrase 4/CA4 (CA4 Products)
- Synonyms
- CAIV Protein, Car4 Protein, RP17 Protein, AW456718 Protein, Ca4 Protein, ca4 Protein, caiv Protein, car4 Protein, rp17 Protein, CA4 Protein, zgc:171842 Protein, carbonic anhydrase 4 Protein, carbonic anhydrase 4 S homeolog Protein, carbonic anhydrase IV a Protein, CA4 Protein, Car4 Protein, ca4 Protein, ca4.S Protein, Ca4 Protein, ca4a Protein
- Background
-
Background: Carbonic Anhydrase 4 (CA4) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic anhydrase 4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Carbonic anhydrase 4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It may have a role in inherited renal abnormalities of bicarbonate transport. Furthermore, Carbonic anhydrase 4 is essential for acid overload removal from the retina and retina epithelium and acid release in the choriocapillaris.
Synonym: Carbonic Anhydrase 4, Carbonate Dehydratase IV, Carbonic Anhydrase IV, CA-IV, CA4,CAIV,Car4,RP17
- Molecular Weight
- 31.4 kDa
- UniProt
- P22748
-