CREB3L1 Protein (AA 396-519) (His tag)
-
- Target See all CREB3L1 Proteins
- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 396-519
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CREB3L1 protein is labelled with His tag.
- Purpose
- Recombinant Human CREB3L1/OASIS Protein (aa 396-519, His Tag)
- Sequence
- Glu396-Ser519
- Characteristics
- A DNA sequence encoding the human CREB3L1 (Q96BA8-1) (Glu396-Ser519) was expressed with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CREB3L1 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, PH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
- Alternative Name
- CREB3L1/OASIS (CREB3L1 Products)
- Synonyms
- CREB3L1 Protein, OASIS Protein, Oasis Protein, diacylglycerol kinase-like Protein, cAMP responsive element binding protein 3 like 1 Protein, cAMP responsive element binding protein 3-like 1 Protein, LOC423198 Protein, CREB3L1 Protein, Creb3l1 Protein
- Background
-
Background: CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis.
Synonym: OASIS,PSEC0238
- Molecular Weight
- 15.2 kDa
- Pathways
- Thyroid Hormone Synthesis, Chromatin Binding
-