Calmegin Protein (CLGN) (His tag)
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- Target See all Calmegin (CLGN) Proteins
- Calmegin (CLGN)
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Calmegin protein is labelled with His tag.
- Purpose
- Recombinant Human Calmegin/CLGN Protein (His Tag)
- Sequence
- Glu20-Trp471
- Characteristics
- Recombinant Human Calmegin is produced by our Mammalian expression system and the target gene encoding Glu20-Trp471 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CLGN Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Calmegin (CLGN)
- Alternative Name
- Calmegin/CLGN (CLGN Products)
- Synonyms
- 4930459O04Rik Protein, AI528775 Protein, Cln Protein, canx Protein, fj49d10 Protein, wu:fj24b04 Protein, wu:fj49d10 Protein, zgc:153946 Protein, CLGN Protein, calmegin Protein, CLGN Protein, Clgn Protein, clgn Protein
- Background
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Background: Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility.
Synonym: Calmegin, CLGN
- Molecular Weight
- 52.9 kDa
- UniProt
- O14967
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