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Calmegin Protein (CLGN) (His tag)

CLGN Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318224
  • Target See all Calmegin (CLGN) Proteins
    Calmegin (CLGN)
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Calmegin protein is labelled with His tag.
    Purpose
    Recombinant Human Calmegin/CLGN Protein (His Tag)
    Sequence
    Glu20-Trp471
    Characteristics
    Recombinant Human Calmegin is produced by our Mammalian expression system and the target gene encoding Glu20-Trp471 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product CLGN Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Calmegin (CLGN)
    Alternative Name
    Calmegin/CLGN (CLGN Products)
    Synonyms
    4930459O04Rik Protein, AI528775 Protein, Cln Protein, canx Protein, fj49d10 Protein, wu:fj24b04 Protein, wu:fj49d10 Protein, zgc:153946 Protein, CLGN Protein, calmegin Protein, CLGN Protein, Clgn Protein, clgn Protein
    Background

    Background: Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility.

    Synonym: Calmegin, CLGN

    Molecular Weight
    52.9 kDa
    UniProt
    O14967
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