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Calcitonin Protein (Calca) (His tag)

Calca Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318223
  • Target See all Calcitonin (Calca) Proteins
    Calcitonin (Calca)
    Protein Type
    Recombinant
    Origin
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Calcitonin protein is labelled with His tag.
    Purpose
    Recombinant Human Calcitonin/CALCA Protein (His Tag, E. coli)
    Sequence
    Tyr58-Asn141
    Characteristics
    Recombinant Human Calcitonin is produced by our E.coli expression system and the target gene encoding Tyr58-Asn141 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product Calca Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,50 % Glycerol, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Calcitonin (Calca)
    Alternative Name
    Calcitonin/CALCA (Calca Products)
    Synonyms
    calcitonin-related polypeptide alpha Protein, CALCA Protein
    Background

    Background: Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

    Synonym: Calcitonin, Katacalcin, Calcitonin Carboxyl-Terminal Peptide, CCP, PDN-21, CALCA, CALC1

    Molecular Weight
    10.5 kDa
    UniProt
    P01258
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