Calcitonin Protein (Calca) (His tag)
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- Target See all Calcitonin (Calca) Proteins
- Calcitonin (Calca)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Calcitonin protein is labelled with His tag.
- Purpose
- Recombinant Human Calcitonin/CALCA Protein (His Tag)
- Sequence
- Ala26-Asn141
- Characteristics
- Recombinant Human Calcitonin is produced by our Mammalian expression system and the target gene encoding Ala26-Asn141 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product Calca Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Calcitonin (Calca)
- Alternative Name
- Calcitonin/CALCA (Calca Products)
- Synonyms
- calcitonin-related polypeptide alpha Protein, CALCA Protein
- Background
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Background: Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Synonym: Calcitonin, Katacalcin, Calcitonin Carboxyl-Terminal Peptide, CCP, PDN-21, CALCA, CALC1
- Molecular Weight
- 13.8 kDa
- UniProt
- P01258
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