VEGFD Protein (His tag)

Catalog No. ABIN7319170

Product Details

Target: VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This VEGFD protein is labelled with His tag.

Purpose: Recombinant Human VEGF-D/VEGFD Protein (His Tag)

Sequence: Phe93-Ser201

Characteristics: Recombinant Human Vascular Endothelial Growth Factor D is produced by our Mammalian expression system and the target gene encoding Phe93-Ser201 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))

Alternative Name: VEGF-D/VEGFD (Figf Products)

Synonyms: FIGF Protein, vegfd Protein, vegf-d Protein, VEGFD Protein, AI325264 Protein, VEGF-D Protein, Vegfd Protein, Vegf-d Protein, vascular endothelial growth factor D Protein, Vascular endothelial growth factor D Protein, VEGFD Protein, vegfd Protein, vegfd.L Protein, Vegfd Protein

Background:

Background: Vascular endothelial growth factor D (VEGF-D) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. It is highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas. VEGF-D is growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. It undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors.

Synonym: Vascular Endothelial Growth Factor D, VEGF-D, c-Fos-Induced Growth Factor, FIGF, VEGFD

Molecular Weight: 12.2 kDa

UniProt: O43915

Pathways: RTK Signaling