CD79a Protein (His tag)
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- Target See all CD79a (CD79A) Proteins
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CD79a protein is labelled with His tag.
- Purpose
- Recombinant Human CD79A(C-6His)
- Sequence
- Leu33-Arg143
- Characteristics
- Recombinant Human CD79A is produced by our Mammalian expression system and the target gene encoding Leu33-Arg143 is expressed with a 6His tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD79A Protein
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B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-143) protein (His-DYKDDDDK-Strep II Tag)
CD79A Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-143) protein (Fc Tag)CD79A Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-140) protein (GST tag)CD79A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
B-cell antigen receptor complex-associated protein alpha chain (CD79A) protein (Fc Tag,ECD)CD79A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
B-cell antigen receptor complex-associated protein alpha chain (CD79A) (Transcript Variant 1) protein (DYKDDDDK-His Tag)CD79A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Alternative Name
- CD79A (CD79A Products)
- Synonyms
- CD79A Protein, Ig-alpha Protein, Iga Protein, Igalpha Protein, Ly-54 Protein, Ly54 Protein, mb-1 Protein, IGA Protein, MB-1 Protein, IG-alpha Protein, CD79a molecule Protein, CD79A antigen (immunoglobulin-associated alpha) Protein, Cd79a molecule-like Protein, CD79A Protein, Cd79a Protein, Cd79al Protein
- Background
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Background: CD79A (also known as Mb-1, Ig alpha and B cell antigen receptor complex-associated protein alpha-chain) is a 30-40 kDa member of the Ig-Superfamily. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Synonym: CD79A antigen, CD79a antigen, CD79A, MB1, MB-1
- Molecular Weight
- 13.4 kDa
- UniProt
- P11912
- Pathways
- BCR Signaling
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