ATG10 Protein (T7 tag,His tag)
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- Target See all ATG10 Proteins
- ATG10 (Autophagy Related 10 (ATG10))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ATG10 protein is labelled with T7 tag,His tag.
- Purpose
- Recombinant Human ATG10 Protein (His&T7 Tag)
- Sequence
- Met 1-Thr190
- Characteristics
- Recombinant Human Autophagy Related 10 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Thr190 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ATG10 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- ATG10 (Autophagy Related 10 (ATG10))
- Alternative Name
- ATG10 (ATG10 Products)
- Synonyms
- APG10 Protein, APG10L Protein, pp12616 Protein, Atg10 Protein, ATG10 Protein, MGC123341 Protein, im:7153729 Protein, zgc:123341 Protein, ATATG10 Protein, autophagy 10 Protein, DDBDRAFT_0190076 Protein, DDBDRAFT_0252608 Protein, DDB_0190076 Protein, DDB_0252608 Protein, 5330424L23Rik Protein, 5430428K15Rik Protein, AI852123 Protein, Agp10 Protein, Apg10l Protein, Apg10p Protein, Atg10l Protein, autophagy related 10 Protein, autophagy-related 10 Protein, AuTophaGy (yeast Atg homolog) Protein, ATG10 autophagy related 10 homolog (S. cerevisiae) Protein, autophagocytosis-associated family protein Protein, E2-like conjugating enzyme Protein, hypothetical protein Protein, autophagy protein 10 Protein, autophagy-related protein 10 Protein, ATG10 Protein, Atg10 Protein, atg-10 Protein, atg10 Protein, CAALFM_C302930WA Protein, APG10 Protein
- Background
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Background: Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28 kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.
Synonym: Ubiquitin-Like-Conjugating Enzyme ATG10, Autophagy-Related Protein 10, APG10-Like, ATG10
- Molecular Weight
- 24.5 kDa
- UniProt
- Q9H0Y0
- Pathways
- ER-Nucleus Signaling, Autophagy
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