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ATG5 Protein

ATG5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.

Catalog No. ABIN7318187

Datasheet as PDF

Target See all ATG5 Proteins

ATG5 (ATG5 Autophagy Related 5 (ATG5))

Protein Type

Recombinant
Origin
7

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Human
Source
15

4

2

1

1
Escherichia coli (E. coli)

Purpose

Recombinant Human ATG5 Protein

Sequence

Met 1-Asp275

Characteristics

Recombinant Human Autophagy Related 5 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp275 is expressed.

Purity

> 90 % as determined by reducing SDS-PAGE.

Endotoxin Level

< 1.0 EU per μg as determined by the LAL method.

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ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein
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ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein (His tag)
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ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein (Strep Tag)
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ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein (Strep Tag)
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ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein (His tag)
ATG5 Origin: Human, Mouse Host: Escherichia coli (E. coli) Recombinant ~95 % ELISA, WB, MS, Neut

ATG5 Autophagy Related 5 (ATG5) protein (Myc-DYKDDDDK Tag)
ATG5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

ATG5 Autophagy Related 5 (ATG5) (AA 1-261) protein (His tag)
ATG5 Origin: Schizosaccharomyces pombe Host: Yeast Recombinant > 90 % ELISA

ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein (His tag)
ATG5 Origin: Pig Host: Yeast Recombinant > 90 % ELISA

Restrictions

For Research Use only
Format

Frozen, Liquid

Buffer

Supplied as a 0.2 μm filtered solution of 20 mM Tris,0.2M NaCl,1 mM DTT,40 % glycerol, pH 8.0 .

Storage

-20 °C

Storage Comment

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Target

ATG5 (ATG5 Autophagy Related 5 (ATG5))

Alternative Name

ATG5 (ATG5 Products)

Background

Background: ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
Synonym: Autophagy protein 5, APG5-like, Apoptosis-specific protein, APG5L, ASP, ATG5,

Molecular Weight

32.4 kDa

UniProt

Q9H1Y0

Pathways

Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy