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Arylsulfatase A Protein (ARSA) (His tag)

ARSA Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318179
  • Target See all Arylsulfatase A (ARSA) Proteins
    Arylsulfatase A (ARSA)
    Protein Type
    Recombinant
    Origin
    • 12
    • 2
    Human
    Source
    • 6
    • 4
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Arylsulfatase A protein is labelled with His tag.
    Purpose
    Recombinant Human Arylsulfatase A/ARSA Protein (His Tag)
    Sequence
    Arg19-Ala507
    Characteristics
    Recombinant Human Arylsulfatase A is produced by our Mammalian expression system and the target gene encoding Arg19-Ala507 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ARSA Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Arylsulfatase A (ARSA)
    Alternative Name
    Arylsulfatase A/ARSA (ARSA Products)
    Synonyms
    ARSA Protein, zgc:101575 Protein, arsa Protein, AS-A Protein, ASA Protein, AW212749 Protein, As-2 Protein, As2 Protein, TISP73 Protein, MLD Protein, mld Protein, arylsulfatase A Protein, arylsulfatase Protein, arylsulfatase A, gene 1 S homeolog Protein, ARSA Protein, arsa Protein, arsA Protein, RB6599 Protein, Arsa Protein, arsa.1.S Protein
    Background

    Background: Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.

    Synonym: Arylsulfatase A, ASA, Cerebroside-Sulfatase, ARSA

    Molecular Weight
    52.9 kDa
    UniProt
    P15289
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