AGR2 Protein (His tag)
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- Target See all AGR2 Proteins
- AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This AGR2 protein is labelled with His tag.
- Purpose
- Recombinant Human AGR2 Protein (His Tag)
- Sequence
- Arg21-Leu175
- Characteristics
- Recombinant Human Anterior Gradient Protein 2 Homolog is produced by our Mammalian expression system and the target gene encoding Arg21-Leu175 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AGR2 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,200 mM NaCl,10 % Glycerol, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))
- Alternative Name
- AGR2 (AGR2 Products)
- Synonyms
- AG2 Protein, GOB-4 Protein, HAG-2 Protein, PDIA17 Protein, XAG-2 Protein, Agr2h Protein, Gob-4 Protein, mAG-2 Protein, wu:fj29g05 Protein, zgc:112187 Protein, agr2 Protein, hag3 Protein, hag-3 Protein, bcmp11 Protein, MGC89004 Protein, XAgr2 Protein, agr2-A Protein, anterior gradient 2, protein disulphide isomerase family member Protein, anterior gradient 2 Protein, anterior gradient 3, protein disulphide isomerase family member Protein, anterior gradient 2, protein disulphide isomerase family member S homeolog Protein, AGR2 Protein, Agr2 Protein, agr2 Protein, agr3 Protein, agr2.S Protein
- Background
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Background: Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94 % aa identity with mouse AGR2.
Synonym: Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2
- Molecular Weight
- 18.9 kDa
- UniProt
- O95994
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