Annexin VIII Protein (His tag)
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- Target See all Annexin VIII (ANXA8) Proteins
- Annexin VIII (ANXA8) (Annexin A8 (ANXA8))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Annexin VIII protein is labelled with His tag.
- Purpose
- Recombinant Human Annexin A8/ANXA8 Protein (His Tag)
- Sequence
- Met 1-Pro327
- Characteristics
- A DNA sequence encoding the human ANXA8 (AAH73755.1) (Met1-Pro327) was expressed with a polyhistidine tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ANXA8 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Annexin VIII (ANXA8) (Annexin A8 (ANXA8))
- Alternative Name
- Annexin A8/ANXA8 (ANXA8 Products)
- Synonyms
- ANX8 Protein, ANXA8L1 Protein, ANXA8L2 Protein, AI466995 Protein, Anx8 Protein, anx8 Protein, MGC85309 Protein, ANXA8 Protein, annexin A8 Protein, annexin A8 S homeolog Protein, ANXA8 Protein, Anxa8 Protein, anxa8.S Protein, LOC694628 Protein, LOC100052045 Protein
- Background
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Background: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.
Synonym: Annexin A8, Annexin VIII, Annexin-8, Vascular Anticoagulant-Beta, VAC-Beta, ANXA8, ANX8
- Molecular Weight
- 39.1 kDa
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