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Angiopoietin 1 Protein (ANGPT1) (Fc Tag)

ANGPT1 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319856
  • Target See all Angiopoietin 1 (ANGPT1) Proteins
    Angiopoietin 1 (ANGPT1)
    Protein Type
    Recombinant
    Origin
    • 12
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    Human
    Source
    • 19
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Angiopoietin 1 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human Angiopoietin-1/ANG1 (N-Fc)
    Sequence
    Asp256-Phe498
    Characteristics
    Recombinant Human Angiopoietin-1 is produced by our Mammalian expression system and the target gene encoding Asp256-Phe498 is expressed with a Fc tag at the N-terminus.
    Purity
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ANGPT1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Angiopoietin 1 (ANGPT1)
    Alternative Name
    Angiopoietin-1/ANG1 (ANGPT1 Products)
    Synonyms
    AGP1 Protein, AGPT Protein, ANG1 Protein, 1110046O21Rik Protein, Ang-1 Protein, Ang1 Protein, Agpt Protein, Agpt1 Protein, ang1 Protein, wu:fc76g06 Protein, ANG-1 Protein, angpt1 Protein, MGC80788 Protein, angiopoietin 1 Protein, angiopoietin 1 S homeolog Protein, ANGPT1 Protein, Angpt1 Protein, angpt1 Protein, angpt1.S Protein
    Background

    Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.

    Synonym: AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, Angiopoietin-1, ANGPT1

    Molecular Weight
    53.9 kDa
    UniProt
    Q15389
    Pathways
    RTK Signaling, Glycosaminoglycan Metabolic Process
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