APLP1 Protein (AA 1-580) (His tag)
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- Target See all APLP1 Proteins
- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-580
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This APLP1 protein is labelled with His tag.
- Purpose
- Recombinant Human APLP-1 Protein (aa 1-580, His Tag)
- Sequence
- Met 1-Glu580
- Characteristics
- A DNA sequence encoding the human APLP1 (P51693-1) (Met1-Glu580) was expressed with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product APLP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, PH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
- Alternative Name
- APLP-1 (APLP1 Products)
- Synonyms
- aplp Protein, MGC115336 Protein, APLP Protein, Aplp1_retired Protein, RGD1561211 Protein, amyloid beta precursor like protein 1 Protein, amyloid beta precursor like protein 1 L homeolog Protein, amyloid beta (A4) precursor-like protein 1 Protein, APLP1 Protein, aplp1.L Protein, aplp1 Protein, Aplp1 Protein
- Background
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Background: APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
Synonym: Amyloid-like protein 1, APLP, APLP-1, C30, APLP1
- Molecular Weight
- 61.9 kDa
- Pathways
- cAMP Metabolic Process
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