alpha 2 Antiplasmin Protein (Fc Tag)
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- Target See all alpha 2 Antiplasmin (SERPINF2) Proteins
- alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This alpha 2 Antiplasmin protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse SerpinF2/SERPINF2 Protein (Fc Tag)
- Sequence
- Val28-Lys491
- Characteristics
- Recombinant Mouse Serine Protease Inhibitor-clade F2 is produced by our Mammalian expression system and the target gene encoding Val28-Lys491 is expressed with a Fc tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SERPINF2 Protein
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Alpha2 Antiplasmin (SERPINF2) (AA 28-491) protein (His tag)
SERPINF2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Alpha2 Antiplasmin (SERPINF2) (AA 27-490) protein (His tag)SERPINF2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Alpha2 Antiplasmin (SERPINF2) (AA 28-491) protein (His tag)SERPINF2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Alpha2 Antiplasmin (SERPINF2) (AA 380-491) protein (His-IF2DI Tag)SERPINF2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Alpha2 Antiplasmin (SERPINF2) (AA 1-491) protein (GST tag)SERPINF2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Alpha2 Antiplasmin (SERPINF2) (Active) protein (His tag)SERPINF2 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,20 % glycerol,1 mM DTT, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
- Alternative Name
- SerpinF2/SERPINF2 (SERPINF2 Products)
- Synonyms
- A2AP Protein, AAP Protein, ALPHA-2-PI Protein, API Protein, PLI Protein, serpin Protein, AI747498 Protein, Pli Protein, Serpimf2 Protein, serpinf2 Protein, serpinf2l Protein, wu:fd57d08 Protein, Dmrs91 Protein, Pedf Protein, serpin family F member 2 Protein, serpin family F member 1 Protein, serine (or cysteine) peptidase inhibitor, clade F, member 2 Protein, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a Protein, SERPINF2 Protein, Serpinf2 Protein, SERPINF1 Protein, serpinf2a Protein, Serpinf1 Protein
- Background
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Background: Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.
Synonym: Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2, Serpinf2
- Molecular Weight
- 79.3 kDa
- UniProt
- Q61247
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
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