ALDH1A1 Protein (His tag)
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- Target See all ALDH1A1 Proteins
- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ALDH1A1 protein is labelled with His tag.
- Purpose
- Recombinant Human ALDH1A1/ALDC Protein (His Tag)
- Sequence
- Met 1-Ser501
- Characteristics
- Recombinant Human Aldehyde Dehydrogenase Family 1 Member A1 is produced by our E.coli expression system and the target gene encoding Met1-Ser501 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ALDH1A1 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
- Alternative Name
- ALDH1A1/ALDC (ALDH1A1 Products)
- Synonyms
- ALDC Protein, ALDH-E1 Protein, ALDH1 Protein, ALDH11 Protein, PUMB1 Protein, RALDH1 Protein, AL1A1 Protein, aldc Protein, aldh-e1 Protein, aldh1 Protein, aldh11 Protein, pumb1 Protein, raldh1 Protein, GGADHR Protein, ALDH1A1 Protein, ALDDH Protein, Ahd2 Protein, Aldh1 Protein, Aldh2 Protein, Ahd-2 Protein, Aldh1a2 Protein, E1 Protein, Raldh1 Protein, Aldh1a1 Protein, ALHDII Protein, RALDH 1 Protein, RalDH1 Protein, aldehyde dehydrogenase 1 family member A1 Protein, aldehyde dehydrogenase 1 family, member A1 Protein, aldehyde dehydrogenase 1 family member A1 L homeolog Protein, aldehyde dehydrogenase family 1, subfamily A1 Protein, aldehyde dehydrogenase Protein, retinal dehydrogenase 1 Protein, ALDH1A1 Protein, aldh1a1 Protein, Aldh1a1 Protein, aldh1a1.L Protein, aldH1 Protein, LOC100732581 Protein, LOC101822890 Protein
- Background
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Background: Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties and subcellular localizations. ALDH1A1 is the main cytosolic isoform, which has a lower affinity for aldehydes than the mitochondrial enzyme. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid.
Synonym: Retinal Dehydrogenase 1, RALDH 1, RalDH1, ALDH-E1, ALHDII, Aldehyde Dehydrogenase Family 1 Member A1, Aldehyde Dehydrogenase Cytosolic, ALDH1A1, ALDC, ALDH1, PUMB10,ALDH11,HEL-9,HEL-S-53e,HEL12,PUMB1,RALDH1
- Molecular Weight
- 57.0 kDa
- UniProt
- P00352
- Pathways
- Dopaminergic Neurogenesis
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