ART4 Protein (Fc Tag)
-
- Target See all ART4 Proteins
- ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))
- Protein Type
- Recombinant
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ART4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse ART4/CD297 Protein (Fc Tag)
- Sequence
- Met1-Lys263
- Characteristics
- A DNA sequence encoding the mouse Art4 (NP_080915.1) (Met1-Lys263) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 91 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product ART4 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))
- Alternative Name
- ART4/CD297 (ART4 Products)
- Synonyms
- ARTC4 Protein, CD297 Protein, DO Protein, DOK1 Protein, ATR4 Protein, 4432404K01Rik Protein, Dombrock Protein, ADP-ribosyltransferase 4 (Dombrock blood group) Protein, ADP-ribosyltransferase 4 Protein, ART4 Protein, Art4 Protein
- Background
-
Background: ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier molecule and CD297, is a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. ART4 could be detected on HEL cells and erythrocytes by FACS analysis while it was absent from activated monocytes, despite the presence of ART4 mRNA in these cells. ART is also known as the carrier of the Dombrock blood group alloantigens (Do) which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane.
Synonym: 4432404K01Rik,ARTC4,DO,DOK1
- Molecular Weight
- 53.7 kDa
- NCBI Accession
- NP_080915
-