ADIPOQ Protein (His tag)

Catalog No. ABIN7320468

Product Details

Target: ADIPOQ (Adiponectin (ADIPOQ))

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ADIPOQ protein is labelled with His tag.

Purpose: Recombinant Mouse Adiponectin/AdipoQ Protein (E.coli, His Tag)

Sequence: Glu18-Asn247

Characteristics: Recombinant Mouse Adipocyte complement-related 30 kDa protein is produced by our E.coli expression system and the target gene encoding Glu18-Asn247 is expressed with a 6His tag at the N-terminus.

Purity: > 95 % as determined by SDS-PAGE

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: ADIPOQ (Adiponectin (ADIPOQ))

Alternative Name: Adiponectin/AdipoQ (ADIPOQ Products)

Synonyms: ADP Protein, DCAF9 Protein, 6720489L24Rik Protein, 9330209L04Rik Protein, Adp Protein, Mamdc1 Protein, RNSVSP4U Protein, SVSIV1 Protein, Svp4 Protein, ACDC Protein, ACRP30 Protein, ADIPQTL1 Protein, ADPN Protein, APM-1 Protein, APM1 Protein, GBP28 Protein, apM-1 Protein, 30kDa Protein, APN Protein, Acdc Protein, Acrp30 Protein, Ad Protein, adipo Protein, apM1 Protein, ADN Protein, acrpl Protein, adipo-b Protein, adipoql Protein, zgc:153584 Protein, adipoq Protein, WD and tetratricopeptide repeats 1 Protein, MAM domain containing glycosylphosphatidylinositol anchor 2 Protein, seminal vesicle secretory protein 4 Protein, adiponectin, C1Q and collagen domain containing Protein, adiponectin, C1Q and collagen domain containing, b Protein, adiponectin, C1Q and collagen domain containing L homeolog Protein, WDTC1 Protein, Mdga2 Protein, Svs4 Protein, ADIPOQ Protein, Adipoq Protein, adipoqb Protein, adipoq.L Protein

Background:

Background: Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.

Synonym: Adiponectin, 30 kDa Adipocyte Complement-Related Protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and Collagen Domain-Containing Protein, Adipose Most Abundant Gene Transcript 1 Protein, apM-1, Gelatin-Binding Protein, ADIPOQ

Molecular Weight: 27.2 kDa

UniProt: Q60994