14-3-3 eta Protein (YWHAH) (GST tag)

Catalog No. ABIN7317744

Product Details

Target: 14-3-3 eta (YWHAH)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This 14-3-3 eta protein is labelled with GST tag.

Purpose: Recombinant Human 14-3-3 eta/YWHAH Protein (GST Tag)

Sequence: Gly 2-Asn 246

Characteristics: A DNA sequence encoding the human YWHAH (Q04917) (Gly 2-Asn 246) was fused with the GST tag at the N-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 0.15M NaCl, 20 mM GST, pH 8.0

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: 14-3-3 eta (YWHAH)

Alternative Name: 14-3-3 eta/YWHAH (YWHAH Products)

Synonyms: ywha1 Protein, 14-3-3e Protein, YWHAH Protein, YWHA1 Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta L homeolog Protein, YWHAH Protein, ywhah Protein, Ywhah Protein, ywhah.L Protein

Background:

Background: YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on chromosome 22q12.3, a region which has been implicated by linkage studies in both BP and schizophrenia.

Synonym: YWHA1

Molecular Weight: 55 kDa

UniProt: Q04917

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction