GPC1 Protein (Ser486Ala-Mutant, Ser488Ala-Mutant, Ser490Ala-Mutant) (His tag)
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- Target See all GPC1 Proteins
- GPC1 (Glypican 1 (GPC1))
- Protein Type
- Recombinant
- Protein Characteristics
- Ser486Ala-Mutant, Ser488Ala-Mutant, Ser490Ala-Mutant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GPC1 protein is labelled with His tag.
- Purpose
- Human Glypican 1 / GPC1 (S486A, S488A, S490A) Protein, His Tag (MALS verified)
- Sequence
- Asp 24 - Ser 530
- Characteristics
- Human Glypican 1 (S486A, S488A, S490A), His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 24 - Ser 530 (Accession # P35052-1 (S486A, S488A, S490A).
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Grade
- MALS verified
- Top Product
- Discover our top product GPC1 Protein
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- Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 57.9 kDa. The protein migrates as 58-61 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- GPC1 (Glypican 1 (GPC1))
- Alternative Name
- Glypican 1 / GPC1 (GPC1 Products)
- Synonyms
- gpc1 Protein, zgc:63947 Protein, GPC1 Protein, Glypican-1 Protein, glypican Protein, AI462976 Protein, HSPG M12 Protein, HSPGM12 Protein, glypican 1b Protein, glypican 1 Protein, gpc1b Protein, GPC1 Protein, gpc1 Protein, Gpc1 Protein
- Background
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Synonyms: Glypican 1,GPC1,
Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. - Molecular Weight
- 57.9 kDa
- NCBI Accession
- NP_002072
- Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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