IFN-alpha/beta R1 protein (His tag)
Origin: Mouse
Host: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
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- Target
- IFN-alpha/beta R1
- Protein Type
- Recombinant
- Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Mouse IFN-alpha / beta R1 Protein, His Tag
- Sequence
- Glu 27 - Thr 429
- Characteristics
- Mouse IFN-alpha / beta R1, His Tag (IF1-M5225) is expressed from human 293 cells (HEK293). It contains AA Glu 27 - Thr 429 (Accession # P33896-1).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.6 kDa. The protein migrates as 57-66 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- IFN-alpha/beta R1
- Alternative Name
- IFN-alpha / beta R1
- Background
-
Synonyms: IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1,
Description: Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway. - Molecular Weight
- 47.6 kDa
- NCBI Accession
- NP_034638
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