MASP1 Protein (AA 450-721) (His tag)
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- Target See all MASP1 Proteins
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 450-721
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MASP1 protein is labelled with His tag.
- Purpose
- Human MASP3 (450-721) Protein, His Tag (active enzyme)
- Sequence
- Ile 450 - Val 721
- Characteristics
- Human MASP3 (450-721), His Tag (MA3-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 450 - Val 721 (Accession # P48740-2).
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MASP1 Protein
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- Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 31.6 kDa. The protein migrates as 38-45 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- Alternative Name
- MASP3 (MASP1 Products)
- Synonyms
- AW048060 Protein, CCPII Protein, Crarf Protein, Masp1/3 Protein, 3MC1 Protein, CRARF Protein, CRARF1 Protein, MAP1 Protein, MASP Protein, MASP3 Protein, MAp44 Protein, PRSS5 Protein, RaRF Protein, mannan-binding lectin serine peptidase 1 Protein, mannan binding lectin serine peptidase 1 Protein, Masp1 Protein, MASP1 Protein
- Background
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Synonyms: MASP3, MASP1, CRARF1, RaRF,
Description: MASP3 is a member of the MASP family. The MASP family proteins were rst discovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associated serine proteases, but later, they were found to interact with colins, and later still, collectin-10 and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includes non-enzymatic factors (MAp19, MAp44). In this review, the association-specic factors of the lectin pathway with haematologic malignancies and related infections are discussed. - Molecular Weight
- 31.6 kDa
- NCBI Accession
- NP_624302
- Pathways
- Complement System
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