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MASP1 Protein (AA 450-721) (His tag)

MASP1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN7199429
  • Target See all MASP1 Proteins
    MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 450-721
    Origin
    • 8
    • 1
    Human
    Source
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MASP1 protein is labelled with His tag.
    Purpose
    Human MASP3 (450-721) Protein, His Tag (active enzyme)
    Sequence
    Ile 450 - Val 721
    Characteristics
    Human MASP3 (450-721), His Tag (MA3-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 450 - Val 721 (Accession # P48740-2).
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
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    Discover our top product MASP1 Protein
  • Application Notes
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 31.6 kDa. The protein migrates as 38-45 kDa under reducing (R) condition due to glycosylation.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 150 mM NaCl, pH 7.5
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
    Alternative Name
    MASP3 (MASP1 Products)
    Synonyms
    AW048060 Protein, CCPII Protein, Crarf Protein, Masp1/3 Protein, 3MC1 Protein, CRARF Protein, CRARF1 Protein, MAP1 Protein, MASP Protein, MASP3 Protein, MAp44 Protein, PRSS5 Protein, RaRF Protein, mannan-binding lectin serine peptidase 1 Protein, mannan binding lectin serine peptidase 1 Protein, Masp1 Protein, MASP1 Protein
    Background
    Synonyms: MASP3, MASP1, CRARF1, RaRF,
    Description: MASP3 is a member of the MASP family. The MASP family proteins were rst discovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associated serine proteases, but later, they were found to interact with colins, and later still, collectin-10 and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includes non-enzymatic factors (MAp19, MAp44). In this review, the association-specic factors of the lectin pathway with haematologic malignancies and related infections are discussed.
    Molecular Weight
    31.6 kDa
    NCBI Accession
    NP_624302
    Pathways
    Complement System
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