hCoV-OC43 Spike Protein (His tag)
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- Target See all hCoV-OC43 Spike (HCoV-OC43 S) products
- hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))
- Protein Type
- Recombinant
- Origin
- Human Coronavirus OC43 (HCoV-OC43)
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Source
- Insect Cells
- Purification tag / Conjugate
- This hCoV-OC43 Spike protein is labelled with His tag.
- Purpose
- HCoV-OC43 Spike protein, His Tag
- Sequence
- Ala 14 - Pro 1297 (RRSRG 754-758 GGSGG)
- Specificity
- HCoV-OC43 Spike protein
- Characteristics
- HCoV-OC43 Spike protein, His Tag (SPN-H52Hz) is expressed from Baculovirus-Insect cells. It contains AA Ala 14 - Pro 1297 (RRSRG 754-758 GGSGG) (Accession # P36334-1).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 148.3 kDa. The protein migrates as 150 kDa under reducing (R) condition .
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))
- Alternative Name
- HCoV-OC43 Spike protein (HCoV-OC43 S Products)
- Background
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Synonyms: Spike,S protein,Spike glycoprotein,S glycoprotein,
Description: Human coronavirus OC43 (HCoV-OC43) is one of seven known coronaviruses to infect humans, which is responsible for the common cold and may have been responsible for the 1889-1890 pandemic. The infecting coronavirus is an enveloped, positive-sense, single-stranded RNA virus that enters its host cell by binding to the N-acetyl-9-O-acetylneuraminic acid receptor. The spike protein of HCoV-OC43 is a trimer protruding from the viral membrane to engage cellular receptors and mediate viral fusion with host membranes. Each spike trimer contains two large regions: N-terminal S1 responsible for receptor binding and C-terminal S2 responsible for fusion. - Molecular Weight
- 148.3 kDa
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