SLC39A6 Protein (AVI tag,Biotin)
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- Target See all SLC39A6 Proteins
- SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))
- Protein Type
- Recombinant
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SLC39A6 protein is labelled with AVI tag,Biotin.
- Purpose
- Biotinylated Cynomolgus LIV-1 / SLC39A6 Protein, His,Avitag™
- Sequence
- Leu 21 - Ile 309
- Characteristics
- Biotinylated Cynomolgus LIV-1, His,Avitag (LV1-C82E5) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Ile 309 (Accession # XP_005586923.1).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SLC39A6 Protein
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- Application Notes
- This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.2 kDa. The protein migrates as 50-65 kDa under reducing (R) condition due to glycosylation.
- Comment
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Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))
- Alternative Name
- LIV-1 / SLC39A6 (SLC39A6 Products)
- Synonyms
- liv1 Protein, wu:fc25a09 Protein, ZIP6 Protein, Ermelin Protein, LIV-1 Protein, solute carrier family 39 (zinc transporter), member 6 Protein, solute carrier family 39 member 6 Protein, solute carrier family 39 (metal ion transporter), member 6 Protein, slc39a6 Protein, SLC39A6 Protein, Slc39a6 Protein
- Background
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Synonyms: SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6,
Description: LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines. - Molecular Weight
- 36.2 kDa
- NCBI Accession
- XP_005586923
- Pathways
- Transition Metal Ion Homeostasis
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