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SLC39A6 Protein (AVI tag,Biotin)

SLC39A6 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7199015
  • Target See all SLC39A6 Proteins
    SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 1
    • 1
    Cynomolgus
    Source
    • 9
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SLC39A6 protein is labelled with AVI tag,Biotin.
    Purpose
    Biotinylated Cynomolgus LIV-1 / SLC39A6 Protein, His,Avitag™
    Sequence
    Leu 21 - Ile 309
    Characteristics
    Biotinylated Cynomolgus LIV-1, His,Avitag (LV1-C82E5) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Ile 309 (Accession # XP_005586923.1).
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SLC39A6 Protein
  • Application Notes
    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.2 kDa. The protein migrates as 50-65 kDa under reducing (R) condition due to glycosylation.
    Comment

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))
    Alternative Name
    LIV-1 / SLC39A6 (SLC39A6 Products)
    Synonyms
    liv1 Protein, wu:fc25a09 Protein, ZIP6 Protein, Ermelin Protein, LIV-1 Protein, solute carrier family 39 (zinc transporter), member 6 Protein, solute carrier family 39 member 6 Protein, solute carrier family 39 (metal ion transporter), member 6 Protein, slc39a6 Protein, SLC39A6 Protein, Slc39a6 Protein
    Background
    Synonyms: SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6,
    Description: LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.
    Molecular Weight
    36.2 kDa
    NCBI Accession
    XP_005586923
    Pathways
    Transition Metal Ion Homeostasis
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