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CD276 Protein (CD276) (AA 29-244) (Fc Tag)

CD276 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092853
  • Target See all CD276 Proteins
    CD276
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-244
    Origin
    • 24
    • 8
    • 3
    • 2
    Mouse
    Source
    • 26
    • 4
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD276 protein is labelled with Fc Tag.
    Purpose
    Recombinant mouse B7-H3 protein with C-terminal human Fc tag
    Specificity
    Mouse B7-H3 (Val29-Phe244) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CD276 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    CD276
    Alternative Name
    B7-H3 (CD276 Products)
    Synonyms
    sc:d0645 Protein, zgc:158279 Protein, 6030411F23Rik Protein, AU016588 Protein, B7RP-2 Protein, B7h3 Protein, B7H3 Protein, 4Ig-B7-H3 Protein, B7-H3 Protein, CD276 molecule Protein, CD276 molecule S homeolog Protein, CD276 antigen Protein, Cd276 molecule Protein, CD276 Protein, cd276.S Protein, cd276 Protein, Cd276 Protein
    Background
    Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    predicted molecular mass of 28.7 kDa after removal of the signal peptide.The apparent molecular mass of mB7-H3-hFc is 55-70 kDa due to glycosylation.
    UniProt
    Q8VE98
    Pathways
    Cancer Immune Checkpoints
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