IGFBP7 Protein (AA 30-282) (His tag)
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- Target See all IGFBP7 Proteins
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-282
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IGFBP7 protein is labelled with His tag.
- Purpose
- Recombinant human IGFBP7 protein with N-terminal 6xHis tag
- Specificity
- 6xHis tag IGFBP7 (Asp30-Leu282)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 26-281) protein (His tag)
IGFBP7 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 27-282) protein (His tag)IGFBP7 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- Alternative Name
- IGFBP7 (IGFBP7 Products)
- Synonyms
- zgc:85888 Protein, AGM Protein, FSTL2 Protein, IBP-7 Protein, IGFBP-7 Protein, IGFBP-7v Protein, IGFBPRP1 Protein, MAC25 Protein, PSF Protein, RAMSVPS Protein, TAF Protein, Fstl2 Protein, Mac25 Protein, insulin like growth factor binding protein 7 Protein, insulin-like growth factor binding protein 7 Protein, IGFBP7 Protein, igfbp7 Protein, Igfbp7 Protein
- Background
- This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
- Molecular Weight
- predicted molecular mass of 27.0 kDa after removal of the signal peptide. The apparent molecular mass of His-IGFBP7 is 35-40 kDa due to glycosylation.
- UniProt
- Q16270
- Pathways
- Growth Factor Binding
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