ARHGEF5 Protein (AA 21-295) (His tag)
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- Target See all ARHGEF5 Proteins
- ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-295
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ARHGEF5 protein is labelled with His tag.
- Purpose
- Recombinant human TIM1 protein with C-terminal 6xHis tag
- Specificity
- TIM1 (Ser21-Gly295) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
- Alternative Name
- TIM1 (ARHGEF5 Products)
- Synonyms
- ARHGEF5 Protein, GEF5 Protein, P60 Protein, TIM Protein, TIM1 Protein, 2210412D05Rik Protein, AA717842 Protein, AW495314 Protein, Tim1 Protein, Rho guanine nucleotide exchange factor 5 Protein, rho guanine nucleotide exchange factor 5 Protein, Rho guanine nucleotide exchange factor (GEF) 5 Protein, ARHGEF5 Protein, LOC100414419 Protein, Arhgef5 Protein
- Background
- The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19. [provided by RefSeq, Apr 2015]
- Molecular Weight
- predicted molecular mass of 30.3 kDa after removal of the signal peptide. The apparent molecular mass of TIM1-His is 100-130 kDa due to glycosylation.
- UniProt
- Q96D42
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