GLUT4 Protein (AA 46-78) (Fc Tag)
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- Target See all GLUT4 (SLC2A4) Proteins
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 46-78
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GLUT4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human SLC2A4 with C-terminal human Fc tag
- Specificity
- SLC2A4 (Asn46-Thr78) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product SLC2A4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
- Alternative Name
- SLC2A4 (SLC2A4 Products)
- Synonyms
- GLUT4 Protein, Glut-4 Protein, Glut4 Protein, glut4 Protein, slc2a4 Protein, SLC2A4 Protein, solute carrier family 2 member 4 Protein, solute carrier family 2 (facilitated glucose transporter), member 4 Protein, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog Protein, SLC2A4 Protein, Slc2a4 Protein, GLUT4 Protein, slc2a4.L Protein
- Background
- This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 29.7 kDa after removal of the signal peptide. The apparent molecular mass of SLC2A4-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P14672
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effect
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